Neutrophil apoptosis, proinflammatory mediators and cell counts in bronchiectasis
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چکیده
منابع مشابه
Neutrophil apoptosis, proinflammatory mediators and cell counts in bronchiectasis.
BACKGROUND Lower airway secretions from patients with bronchiectasis show inflammatory cell infiltration and increased proinflammatory mediators. The aim of this study was to investigate the effects of antibiotic treatment for exacerbations on neutrophil apoptosis and necrosis. METHODS Sputum was induced from 15 subjects with idiopathic bronchiectasis at the beginning of an acute exacerbation...
متن کاملAIRWAY BIOLOGY Neutrophil apoptosis, proinflammatory mediators and cell counts in bronchiectasis
Background: Lower airway secretions from patients with bronchiectasis show inflammatory cell infiltration and increased proinflammatory mediators. The aim of this study was to investigate the effects of antibiotic treatment for exacerbations on neutrophil apoptosis and necrosis. Methods: Sputum was induced from 15 subjects with idiopathic bronchiectasis at the beginning of an acute exacerbation...
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BACKGROUND Vascular endothelial growth factor (VEGF; vascular permeability factor) is one of the most potent proangiogenic cytokines, and it plays a central role in mediating the process of angiogenesis or new blood vessel formation. Neutrophils (PMNs) recently have been shown to produce VEGF. HYPOTHESIS The acute inflammatory response is a potent stimulus for PMN-directed angiogenesis. MET...
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Mast cells are able to trigger life-saving immune responses in murine models for acute inflammation. In such settings, several lines of evidence indicate that the rapid and protective recruitment of neutrophils initiated by the release of mast cell-derived pro-inflammatory mediators is a key element of innate immunity. Herein, we investigate the impact of mast cells on critical parameters of ne...
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ژورنال
عنوان ژورنال: Thorax
سال: 2004
ISSN: 0040-6376
DOI: 10.1136/thx.2003.008037